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AGE FEATURES OF THE EXCRETION OF CARBONILIC COMPOUNDS WITH URINE IN CHILDREN IN UNEXPOSED TERRITORY


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Abstract

Introduction. Carbonyl compounds (CC) are pollutants affecting the population and occupying an exceptional position in various fields of human activity. A significant source of CC is tobacco smoke. Material and methods. Urine samples of 278 children were analyzed by the method of gas chromatography. Additionally, there were studied dependencies of the content of the CC on the harmful chemical effects in living conditions: active and passive smoking. The assessment of the effect of smoking on formaldehyde emissions (FD) was carried out using the chi-square test for a 3x3 table. Results. The results obtained on the content of CC in the urine in several age groups. FD concentrations, in general, were shown to be in the range from 1.2 to 207.1 μg/dm3. The highest values were observed in the children’s population of the age group up to 7 years and in the group of 15-17 years. For representatives of the 1st (up to 7 years) and 3rd (15-17 years) age groups, the concentrations of acetaldehyde and acetone were in the range: for acetaldehyde - from 4.0 to 179.7 µg/dm3, acetone - from 0.35 to 11.95 µg/dm3. A statistically significant direct relationship was found between active smoking and FD content in urine (rsp = 0.24, p = 0.033); the reverse is with acetone content (rsp = 0.23, p = 0.042), and the inverse correlation between acetaldehyde content and passive smoking (rsp = 0.23, p = 0.038). Conclusion. The highest content of formaldehyde in the urine was found in groups “up to 7 years old” and “15-17 years old”. No age and gender differences in acetaldehyde and acetone concentrations were found.


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