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CHARACTERISTICS OF B-2 LYMPHOCYTES IN PATIENTS WITH SERONEGATIVE RHEUMATOID ARTHRITIS ARTICULAR FORM


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Abstract

The results of the analysis of the ratio of minor subpopulations of В lymphocytes in seronegative variant of course of the articular form of rheumatoid arthritis. Detected an increase in relative and absolute numbers of subpopulations of В - 1 lymphocytes with the phenotype CD19+CD5+. In the analysis of В-2 cells with immunophenotype CD19+CD5 - shows the increase in the degree of expression of markers of early activation co-stimulatory molecules CD86+, the readiness to apoptosis and the number аpoptygma cells


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