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Modern technologies of ultrasound diagnostics of cirrhosis in chronic liver diseases in children


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Abstract

By methods of ultrasound (US) diagnostics there were examined 177 children at the age offrom 2 months to 17 years, with liver cirrhosis (LC) in the outcome of chronic hepatitis (CH) of various etiologies. It was found that, irrespective of the etiological factor there is noted a large number of general ultrasound characters typical for stages of the formation of the LC: «streaking» of the hepatic image, cirrhotic nodes, splenomegaly and signs ofportal hypertension. The rate of the formation of LC was analyzed in dependence on the etiological factor. It was established that often, and in a short time LS develops in the outcome of CHD, autoimmune hepatitis and cryptogenic chronic hepatitis. In the examination of 135 children there were included invasive (biopsy) and non-invasive ultrasound methodologies for the quantitative assessment of the liver parenchyma structure: Acoustic Structure Quantification (ASQ) and Transient elastography (TEP). Based on a comparative analysis of US and morphological data SP values> 2.77 and elasticity> 13.90 were established to indicate LC (F4) according to METAVIR system. There were established additional diagnostic criteria for the assessment of the severity of the state of LC patients: density index (DI) increased significantly as far as the disease progresses. The use of non-invasive techniques dramatically expands the diagnostic capabilities of a traditional ultrasound examination of the liver.


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