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THE USE OF INTRAVENOUS IMMUNOGLOBULIN PENTAGLOBIN IN THE COMPLEX TREATMENT OF SEVERE COMMUNITY-ACQUIRED PNEUMONIA IN CHILDREN


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Abstract

There are presented data from a comprehensive examination and treatment of 30 children with community-acquired pneumonia (CAP). For the treatment of young children with focal-confluent forms of CAP and the clinical manifestations of infectious-septic shock, Pentaglobin preparations containing IgM were used. Severe CAP with a tendency to destruction was more often observed in cases with the dominance of gram-negative flora in the etiological structure, most often detected in the foothill zone (18.2% of children), in the middle mountain zone - in- 13.3%, in the low-grade zone - in 5% of children. Pseudomonas aeruginosae was more commonly seeded in children in the foothill zone (12.5%), while in children living in the lowland and middle mountain zone in 2.5% and 6.6% correspondingly. The authors showed the preparation of intravenous immunoglobulin Pentoglobin is a safe, effective, easily tolerated means of etiotropic and pathogenetic therapy of severe CAP, caused more often by gram-negative and gram-positive bacterial microbiota.


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