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Vaccination against the new coronavirus infection SARS-CoV-2. The current state of the problem


DOI: https://doi.org/10.46563/1560-9561-2022-25-2-139-146

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Abstract

Vaccines against the new coronavirus infection (COVID-19 or SARS-CoV-2) have been developed at an unprecedented pace since the beginning of the pandemic. Some of them have received permission for mass production already at the stage of clinical trials. COVID vaccines are now being used on a large scale over the world. In the review article describes the characteristics of used both abroad and in Russia COVID vaccines, differed in structure and mechanism of action. The data of clinical research on their efficiency and safety is presented. In modern conditions of a pandemic of a new coronavirus infection, vaccination was shown to be the most effective method of prevention, which can significantly reduce morbidity and mortality due to coronavirus. There are considered such nuances of coronavirus vaccination, as the need for a booster dose, vaccination of children and adolescents. Rare adverse events are described. However, given the relatively small experience and short duration of the use of coronavirus vaccines, there are many questions concerning vaccination of persons with disorders in the immune system, vaccination of infants, the impact of changes in coronavirus strains on the effectiveness of the vaccines used, and many others. All these issues require further research, which continues all over the world. The authors recommend applying the knowledge about COVID vaccines in daily practice, constantly updating them, which will indirectly help to ensure maximum vaccination coverage of the population against coronavirus, including children and adolescents.


Для цитирования: Галицкая М.Г., Фисенко А.П., Макарова С.Г. Вакцинация против новой коронавирусной инфекции SARS-CoV-2. Современное состояние проблемы. Российский педиатрический журнал. 2022; 25(2): 139–146. https://doi.org/10.46563/1560-9561-2022-25-2-139-146

For citation: Galitskaya M.G., Fisenko A.P., Makarova S.G. Vaccination against the new coronavirus infection SARS-CoV-2. The current state of the problem. Rossiyskiy Pediatricheskiy Zhurnal (Russian Pediatric Journal). 2022; 25(2): 139–146. (in Russian). https://doi.org/10.46563/1560-9561-2022-25-2-139-146

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