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The evolution of attitude to participation in clinical trials of anti-HIV/AIDS vaccines in population and development of approaches to formation of volunteers cohorts


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The article presents the results of analysis occurred during last five years in respect of participation in clinical trials of anti-HIV/AIDS vaccines, changing of priorities of motivation, degree of awareness of HIV-infection and means of prevention and treatment, readiness to vaccination against HIV-infection. The prospective approaches to formation of cohorts of volunteers with participation of representatives of population groups with different risk of HIV-infection, including HIV-non-infected partners from discordant pairs. The qualitatively handled selection permits forming a cohort with high level of stability that hereinafter ensures appropriate implementation of clinical trials in given period.

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