L. Sh. Ishberdina, V. B. Malkhanov

Immunogenetic criteria for uveitis development in the population of the Republic of Bashkortostan

Based on the association of certain histocompatibility Class I antigens with uveitis in patients from the Republic Bashkortostan it has been proven that HLA B27 and B47 and haplotype A2B47 should be considered to be the markers responsible for the occurrence of uveitis in systemic and syndromic diseases. The greatest relative risk of herpetic anterior and posterior uveitis is associated with HLA B44 and B51 antigens; the risk of anterior and posterior uveitis is related to HLA B27 and HLA A28, A29 and B53, respectively. The findings permit improvement of the quality of early diagnosis of these diseases and are recommended for use in ophthalmological practice.

Key Words:  antigens, herpetic uveitis, autoimmune component

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