CYTOLOGICAL INDICES OF THE MUCOUS MEMBRANES AND THE ADAPTATION’S STATE OF CHILDREN LIVING IN THE NEIGHBORHOOD OF THE ENTERPRISE - ODOR SOURCE
The work of a number of enterprises is known to be accompanied with emissions into the air of complex multicomponent mixtures with a specific smell, the obsessive effect of which can cause complaints of the population, including various health problems. As a rule, abroad in these cases, only the level of psychological stress (“annoyance”) is evaluated without an objective analysis of the health status, which necessitates the development of a methodology for such analysis. Therefore, the work uses a wide range of health assessment of children: the cytological status of the cheek mucosa on 13 indices, the distribution of children according to three stages of adaptation and medical examinations of specialists to determine the health groups of children in control preschool institutions and preschool institutions located near the enterprise for the production of chewing gum. According to the research of cytological status using the non-invasive method, most of the indices did not differ significantly within the compared groups. The assessment of the health status according to the data of in-depth medical examination by specialists and the distribution by stages of adaptation allowed establishing certain differences in the studied indices in the children’s population, but these differences were assessed as preliminary. Earlier analytical studies have shown that many components forming specific odor emissions of the enterprise have an irritant effect on the mucous membranes of the eyes and upper respiratory tract. Meanwhile, all of them are in concentrations not exceeding their hygienic standards, which may cause the absence of the influence of a weak, barely noticeable odor (no more than 2 points) on the cytological status of children. The need to develop a comprehensive approach to the study of the mechanisms of the development of pathological conditions associated with odor, using multiparameter studies, including the analysis of psycho-emotional status, was shown.
About the authorsBelyaeva Natalia N.
Ryazanov V.A. Basic principles of hygienic regulation of atmospheric pollution. Gigiena i sanitariya. 1949; 5: 3-9. (in Russian)
Haahtela T., Martilla O., Vilkka V. Human health risks caused by poor sulphur compounds in ambient air in South-Karelia, Finland. Man and his Ecosystem: Proc. 8-th World Clean Air Congr. The Hague, 1989; 1: 135-8.
Winneke G., Sucker K., Both R. Population Odour Annoyance is Influenced by the Hedonic Quality of Industrial Odours. Environmental Odour Management, International Conference, Cologne, 17 - 19 November 2004; 9-12.
Radon K., Peters A., Pramk G., Ehrenstein V., Shhulze A., Hehl O., Nowak D et al. Odours from livestock farms and quality of life in the surrounding areas. In: Mezhdunarodnaya konferentsiya «Topical issues of odor assessment and regulation». Sbornik dokladov. 4 oktyabrya 2006g. Moskva. M.: 2006; ZAO «Ligget-Dukat»: 281-8. (in Russian)
Shtaynkhayder B., Bot R., Vinneke G. Field study of industrial odors, irritants, and symptoms of gastric and general malaise. In: Mezhdunarodnaya konferentsiya «Topical issues of odor assessment and regulation». Sbornik dokladov. 4 oktyabrya 2006g. Moskva. M.: 2006; ZAO «Ligget-Dukat»: 225-54. (in Russian)
Sunčič S.V., Hrašovec B., Sabadin A. et al. Influence of industrial odours on the citizens state of health. Man and his Ecosystem: Proc. 8-th World Clean Air Congr. The Hague, 1989; 1: 129-33.
Winneke G. The assessment of the impact of environmental odours in the community. Environmental Odour Management. International Conference, Cologne, 17 - 19 November 2004; 5-7.
Shusterman D. Review of the upper airway, including olfaction, as mediator of symptoms. Environmental Health Perspectives 110 (2002), 649-53.
White M.C., Berger-Frank S.A., Middleton D.C., Falk H. Addressing community concerns about asthma and air toxics. Environmental Health Perspectives. 2002; 110: 561-4.
Horizontal Guidance for Odour. Part 1-Regulation and Allowing. Part 2-Assessment and Control. Draft. IPPC H4. Available at: http://www.sinia.cl/1292/articles-55482_UKEPA_2002_IPPC_H4.pdf
Assessment of community response to odorous emissions. R&D Technical report P4-095/TR, undertaken for the Environment Agency by OdourNet UK Ltd, 2002. [Электронный ресурс]. Режим доступа: https://www.gov.uk/government/uploads/system/uploads/attachment_data/file/290405/sp4-095-tr-e-e.pdf
Sucker K., Muller F., Bischoff M., Both R., Winneke G. Assessment of frequency, intensity and hedonic tone of environmental odours in the field: A comparison of trained and untrained residents. Environmental Odour Management, International Conference, Cologne, 17 - 19 November 2004; 219-28.
Odour management in British Columbia: review and recommendations. Final report. [Электронный ресурс]. - Режим доступа: http://www.cschi.cz/odour/files/world/52_odour_mgt_final_june13_05.pdf
Kutepov E.N., Belyaeva N.N., Charyeva Zh.G., Leshcheva E.P., Shamarin A.A. Evaluation of cytological status of the mucous membrane of the nasal cavity and mouth. Gigiena i sanitariya. 1998; 4: 47-50. (in Russian)
Tulebaev R.K., Ushakov I.S., Kabyldepova G.A. Features of changes in the mucous membrane of the nasal cavity and the paranasal sinuses in gypsum workers. Rossiyskaya rinologiya.1998; 2: 75-6. (in Russian)
Ponomareva O.Yu., Budarina O.V., Belyaeva N.N. Cellular indicators of the respiratory system in the hygienic evaluation of atmospheric air pollution by the substances having odour. Mir nauki, kul’tury, obrazovaniya. 2011; 29 (4): 277-80. (in Russian)
Belyaeva N.N. Cytological status of the mucous membranes of the nose and mouth for monitoring the health status of children of Moscow GOU. «Sovremennye problemy profilakticheskoy i klinicheskoy meditsiny». V kn.: Materialy mezhinstitutskoy nauchno-prakticheskoy konferentsii s mezhdunarodnym uchastiem, posvyashchennoy 65-letiyu so dnya rozhdeniya d.m.n., prof. V.M. Glinenko. Moskva. 5 maya 2014. M.: 2014: 50. (in Russian)
Belyaeva N.N., Sycheva L.P., Zhurkov V.S., Shamarin A.A., Kovalenko M.A., Gasimova Z.M. et al. Metodicheskie rekomendatsii. «Assessment of cytological and cytogenetic status of mucous membranes of the nose and mouth in humans». Utverzhdeny predsedatelem nauchnogo soveta RAMN i MZ i SR Rossii po ekologii cheloveka i gigiene okruzhayushchey sredy akademikom RAMN Rakhmaninym Yu.A. 27 aprelya 2005 g.; 37 p. (in Russian)
Abadzhidi M.A., Molodtsov S.A., Ashkinazi V.I, Salina E.V. Microflora of the buccal epithelium in children, often suffering from respiratory infections. Rossiyskiy pediatricheskiy zhurnal. 2002; 1: 56-7. (in Russian)
Abadzhidi M.A.,Makarova T.V., Majianskaia I.V., Zaslavskaia M.I.,Strochkova Iy.Iy., Majianskij A.M. Buccal epithelial cells as a tool for clinical and laboratory researchs. Nizhegorodskij medicinsrij zhurnal. 2003; 3-4: 8-12. (in Russian)
Baevskiy R.M., Bersen’eva A.P. Introduction to prenosological diagnostics. M.: Slovo; 2008; 217s. (in Russian)
Kurkin A.V., Tuleutayeva S.T., Esimova R.Zh., Kurylenko N.O. The comparative characteristic citogramm bukkalnis epithelium for the first year of orthodontic treatment of anomalies of development in children. International magazine of applied and basic researches 2015; 12(7): 1244-46. https://applied-research.ru/ru/article/view?id=8127
Pinigin M.A., Tepikina L.A., Budarina O.V., Safiulin A.A., Malysheva A.G. Stages of hygienic regulation of volatile components of flavors in the manufacture of chewing gum. Toksikologicheskiy vestnik. 2011; 2: 5-10. (in Russian)
Pinigin M.A., Budarina O.V., Safiulin A.A. Development of bases of regulation and control of odours in ambient air and ways of harmonization in this field. Gigiena i sanitariya. 2012; 5: 72-5. (in Russian)
Budarina O.V., Pinigin M.A., Sabirova Z.F., Fedotova L.A., Potapchenko T.D. Modern methodological approaches to the experimental substantiation of the permissible content of odorous substances in the air. Toksikologicheskiy vestnik. 2017; 4 (145): 34-9. (in Russian)
Pinigin M.A., Tepikina L.A., Budarina O.V. The problem of Odour in the Air and How to Solve it in Russia. Environmental Odour Management. International Conference, Cologne, 17 - 19 November 2004; 563-7.
Air quality guidelines for Europe. Vtoroe izdanie. M.; 2004; 302 p. (in Russian)
Harmful chemicals. Natural organic compounds (Ed. V.A. Filova, Yu.I. Musiychuka, B.A. Ivina). S. Peterburg: 1998; 498 p. (in Russian)
Belyaeva N.N. Assessment of the cytologic status of mucous membranes of a nose and mouth. In: Noninvasive methods in assessment of health of the population. M, Monograph. 2006:151-63
Polyakova V.O., Paltseva E.M., Krulevsky V.A. Bukkalny epithelium. New approaches to molecular diagnosis of socially important pathology. St. Petersburg, publishing house: N-L. 2015:1 28с.
Yurchenko V.V., Podolnaya M.A., Ingel F.I., Krivtsova E.K., Belyaeva N.N., Nedachin A.E. and al. Micronuclear test on bukkalny epiteliotsita. In: Polyorgan micronuclear test in ekologo-hygienic researches. (Ed. Yu.A. Rakhmanin and L.P. Sycheva) M. Monograph. 2007: 220-68.
Sycheva L.P., Byakhova M.M. Cytogenetic damage in buccal epithelium of gastrointestinal cancer patients. Mutagenesis. 2014; 29 (6): 526-7.
Беляева Н.Н., Пономарева О.Ю., Александрова В.П., Олесинов А.А.Бударина О.В., Гасимова З.М. Use of neinvaivny assessment of the cytologic status of a mucous membrane of a nose and mouth in social and hygienic monitoring. Gigiena i sanitariya. 2009; 6: 74-76
Asudov R.L.O., Morozova E.M., Zabolotnay S.V., Mikhalik T.A.,Morozov V.N. N Microscopic features of buccal epithelium in smoking students of Indo-Dravidian race (by E. Hooton) series: Medicine and pharmacy.2015;4 (6): 120-4.
Belyaeva N.N., Pinigin M.A. Budarina O.V., Sabirova Z.F., Rosolovsky A.P. Assessment of the cytologic status and condition of adaptation of the children living in Veliky Novgorod with different extent of air pollution by odorous substances. Materials of the International forum of Scientific council of the Russian Federation “Environmental problems a sovremennosti: vyyavleniye and prevention of an adverse effect of the determined factors and climatic changes on the environment and to health of the population” M.,2017 (Ed. Yu.A. Rakhmanin) ISRN 978-5-95-00159-0-8. 2017: 46-8.
Belyaeva N.N., Pinigin M.A. Budarina O.V., Sabirova Z.F., Rosolovsky A.P. To a question of assessment of a functional condition of the children living in Veliky Novgorod. In the book: The Russian hygiene - developing traditions, directs in the future. Materials X11 of the All-Russian congress of hygienists and health officers.М., 2017: 246-249.
Belyaeva N.N., Pinigin M.A., Budarina 0.V. Cytological status of the buccal mucosa in healthy children living in different climatic and geographic regions. Modern science. (International scientific journal. ISSN 2414-9918). 2017; 2: 277-80.
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