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FEATURES OF THE COURSE OF NEW CORONAVIRUS INFECTION IN NEWBORNS AND FIRST-YEAR INFANTS


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Abstract

The aim of the study was to assess the features of the course of new coronavirus infection in newborns and children of the first year of life. Materials and methods. Thirty-six children aged eight days to 11 months were hospitalized in the covid centre of the National Medical Research Center for Children’s Health (of which nine children were transferred from one of the surgical hospitals in Moscow due to the contact with SARS-CoV-2). Results. Despite severe concomitant surgical pathology in 25% of patients, 98% of children had mild to moderate disease. Febrile temperature (up to a maximum of 39 oC) was observed in 4 infants, sub-febrile temperature in 5 people. In other children, for the entire period of treatment, there was no increase in temperature. Mothers’ complaints about lethargy dominated the clinical picture of the disease, followed by refusal to eat, runny nose, sneezing, swallowing voice, coughing, shortness of breath in their children. During the examination, the following signs were revealed: yawn hyperemia, mucous separated from the nose, hard breathing and dry wheezing (in 1 infant). The general blood test showed anemia (mostly related to prematurity anemia, or iron deficiency anemia), leftward leukocytosis (due to concomitant surgical pathology), leukopenia, various changes in the leukocytic formula of blood. In some instances, thrombocytopenia increased in D-dimer C-RP, procalcitonin, ferritin, bilirubin, and alanine aminotransferase. In only six infants with a moderate disease course, changes characteristic of a new coronavirus infection were identified on the chest CT scan. Six infantas had rhythm disorders detected in electrocardiographic examination (no deviations were found in echocardiographic examination). Conclusion. According to both foreign literature and data obtained during our study, it can be concluded that, compared with adults, infants have a milder course of the disease and less pronounced changes obtained during laboratory and instrumental studies.


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